Molecular Fundamentals of Enzyme Nanogel as a Robust Catalyst
Date: Nov. 13, 2008
Time: 3:00 pm
Place: 136 Ross Hall
Zheng Liu
Professor and Associate Director
Research Institute of Chemical Engineering Science and Technology at
Tsinghua University in China
Biography
Liu obtained his bachelor's, master's and doctoral degrees in chemical engineering
from Tsinghua University in 1987, 1989 and 1993, respectively. He previously worked
as a UNESCO Research Fellow with the Tokyo Institute of Technology and served
as the department chair from 1999 to 2006. His research focuses on chemical and
biomolecular engineering, with special interests in chemical re-engineering of
enzymes for industrial biocatalysis; in vitro protein refolding using chemical
chaperones; molecular imprinting for chiral separation; and bioremediation of
oil and salt contaminated soil. He has published more than 120 peer-reviewed journal
papers and received many international awards. He holds 15 patents.
Abstract
Molecular Fundamentals of Enzyme Nanogel as a Robust Catalyst
Liu will review recent efforts in developing novel methods for protein refolding
and modification, both of which are key steps associated with the transition of
protein conformation. Liu's group designed and fabricated single enzyme nanogels
via aqueous in situ polymerization, which enabled the enzymes to display catalytic
powers at high temperatures and in anhydrous solvents.
